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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F1
All Species:
10.61
Human Site:
S43
Identified Species:
19.44
UniProt:
Q01094
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01094
NP_005216.1
437
46920
S43
I
S
A
A
Q
D
A
S
A
P
P
A
P
T
G
Chimpanzee
Pan troglodytes
XP_524538
437
47536
P24
K
V
V
P
A
M
S
P
T
E
L
W
P
S
G
Rhesus Macaque
Macaca mulatta
XP_001103717
502
53768
S108
I
S
A
A
Q
D
A
S
A
P
P
A
P
T
G
Dog
Lupus familis
XP_542963
571
61192
S178
I
S
T
A
Q
D
A
S
A
P
P
A
P
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61501
430
46305
G41
I
S
T
A
P
D
V
G
A
P
Q
L
P
A
A
Rat
Rattus norvegicus
Q62814
300
33206
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515449
468
50133
A22
P
R
S
L
G
R
A
A
A
G
P
D
L
P
P
Chicken
Gallus gallus
Q90977
403
43534
L21
L
G
G
A
S
P
H
L
L
I
V
S
A
S
E
Frog
Xenopus laevis
NP_001090608
426
47125
T37
Q
Q
I
V
I
I
S
T
P
D
V
P
A
E
A
Zebra Danio
Brachydanio rerio
NP_001074097
429
46452
T41
C
A
V
Y
S
N
A
T
R
I
Q
I
N
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
D79
K
N
E
S
V
D
L
D
Y
D
H
V
L
S
S
Honey Bee
Apis mellifera
XP_396223
416
46049
A42
G
S
L
D
E
V
Q
A
Q
K
V
A
E
E
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001123287
404
44387
I22
T
E
A
K
I
R
T
I
L
G
V
S
P
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.7
86
70.9
N.A.
84.6
23.1
N.A.
39.9
59.9
49.8
37.2
N.A.
20.6
29.7
N.A.
38.4
Protein Similarity:
100
54.4
86.2
72.6
N.A.
88.5
37.9
N.A.
51.2
70
63.3
53.7
N.A.
31.5
46.4
N.A.
54.2
P-Site Identity:
100
13.3
100
86.6
N.A.
46.6
0
N.A.
20
6.6
0
13.3
N.A.
6.6
13.3
N.A.
20
P-Site Similarity:
100
26.6
100
86.6
N.A.
46.6
0
N.A.
33.3
26.6
13.3
33.3
N.A.
26.6
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
24
39
8
0
39
16
39
0
0
31
16
16
16
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
39
0
8
0
16
0
8
0
0
0
% D
% Glu:
0
8
8
0
8
0
0
0
0
8
0
0
8
16
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
8
0
8
0
0
8
0
16
0
0
0
0
39
% G
% His:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% H
% Ile:
31
0
8
0
16
8
0
8
0
16
0
8
0
0
0
% I
% Lys:
16
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
8
0
8
8
0
0
8
8
16
0
8
8
16
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
8
0
0
0
0
0
0
8
0
0
% N
% Pro:
8
0
0
8
8
8
0
8
8
31
31
8
47
8
16
% P
% Gln:
8
8
0
0
24
0
8
0
8
0
16
0
0
0
0
% Q
% Arg:
0
8
0
0
0
16
0
0
8
0
0
0
0
8
0
% R
% Ser:
0
39
8
8
16
0
16
24
0
0
0
16
0
24
8
% S
% Thr:
8
0
16
0
0
0
8
16
8
0
0
0
0
24
8
% T
% Val:
0
8
16
8
8
8
8
0
0
0
31
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _